Calcitonin Gene-Related Peptide Biases Langerhans Cells toward Th2-Type Immunity
Abstract
Langerhans cells (LC) are epidermal dendritic cells capable, in several experimental systems, of Ag-presentation for stimulation of cell-mediated immunity. LC have been considered to play a key role in initiation of cutaneous immune responses. Additionally, administration of donor T cells to bone marrow chimeric mice with persistent host LC, but not mice whose LC have been replaced by donor cells, exhibit marked skin graft-vs-host disease,...
Paper Details
Title
Calcitonin Gene-Related Peptide Biases Langerhans Cells toward Th2-Type Immunity
Published Date
Nov 1, 2008
Journal
Volume
181
Issue
9
Pages
6020 - 6026
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Notes
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