Dose-Dependent Retinal Changes Following Sodium Iodate Administration: Application of Spectral-Domain Optical Coherence Tomography for Monitoring of Retinal Injury and Endogenous Regeneration
Abstract
Background: The purpose of this study was to demonstrate the progression of acute retinal injury by correlating histological sections with in vivo spectral-domain optical coherence tomography (SD-OCT) images.Methods: Male C57BL/6 mice were treated intravenously with two different sodium iodate (NaIO3) doses (35 mg/kg or 15 mg/kg). In vivo SD-OCT was performed up to 3 months post-injury. Ex vivo retinal histology, TUNEL and IsolectinB4...
Paper Details
Title
Dose-Dependent Retinal Changes Following Sodium Iodate Administration: Application of Spectral-Domain Optical Coherence Tomography for Monitoring of Retinal Injury and Endogenous Regeneration
Published Date
Mar 24, 2014
Journal
Volume
39
Issue
10
Pages
1033 - 1041
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