Transforming Growth Factor-β Signaling Pathway in Patients With Kawasaki Disease
Abstract
Transforming growth factor (TGF)-β is a multifunctional peptide that is important in T-cell activation and cardiovascular remodeling, both of which are important features of Kawasaki disease (KD). We postulated that variation in TGF-β signaling might be important in KD susceptibility and disease outcome.We investigated genetic variation in 15 genes belonging to the TGF-β pathway in a total of 771 KD subjects of mainly European descent from the...
Paper Details
Title
Transforming Growth Factor-β Signaling Pathway in Patients With Kawasaki Disease
Published Date
Feb 1, 2011
Volume
4
Issue
1
Pages
16 - 25
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