Original paper
The human WW45 protein enhances MST1-mediated apoptosis in vivo
Abstract
Mammalian sterile 20-like kinase 1 (MST1) is a serine/threonine protein kinase that is activated in response to a variety of apoptotic stimuli and causes apoptosis when over-expressed in mammalian cells. The physiological regulation and cellular targets of MST1 are not well understood. Using a yeast two-hybrid system, we identified human WW45 (hWW45, also called hSav1) as an MST1-binding protein. The association between the two proteins was...
Paper Details
Title
The human WW45 protein enhances MST1-mediated apoptosis in vivo
Published Date
Feb 9, 2009
Volume
23
Issue
3
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Notes
History