Original paper
Oncrasin targets the JNK-NF-κB axis to sensitize glioma cells to TNFα-induced apoptosis
Abstract
Resistance of glioblastoma multiforme (GBM) to tumor necrosis factor (TNF) α-induced apoptosis have been attributed to increased nuclear factor-kappaB (NF-κB) activation. As we have previously reported that certain anticancer chemotherapeutics can sensitize glioma cells to TNFα-induced apoptosis by abrogating NF-κB activation, we investigated the potential of oncrasin in sensitizing glioma cells to TNFα-induced apoptosis. Oncrasin reduced glioma...
Paper Details
Title
Oncrasin targets the JNK-NF-κB axis to sensitize glioma cells to TNFα-induced apoptosis
Published Date
Nov 3, 2012
Journal
Volume
34
Issue
2
Pages
388 - 396
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Notes
History