Improving inhaler technique, adherence to therapy and the precision of dosing: major challenges for pulmonary drug delivery

Introduction: The inhaled route has many advantages, but requires the patient to use, and to master the use of, an inhaler device. Poor inhaler technique and non-adherence to therapy lead to a highly variable lung dose in clinical practice, with subsequent loss of clinical efficacy and wastage of economic resources. Areas covered: This paper discusses problems of poor inhaler technique, non-adherence to inhaler therapy, other issues relating to...