Original paper
Autoimmune Polyendocrine Syndrome Type 1 and NALP5, a Parathyroid Autoantigen
Volume: 358, Issue: 10, Pages: 1018 - 1028
Published: Mar 6, 2008
Abstract
Autoimmune polyendocrine syndrome type 1 (APS-1) is a multiorgan autoimmune disorder caused by mutations in AIRE, the autoimmune regulator gene. Though recent studies concerning AIRE deficiency have begun to elucidate the molecular pathogenesis of organ-specific autoimmunity in patients with APS-1, the autoantigen responsible for hypoparathyroidism, a hallmark of APS-1 and its most common autoimmune endocrinopathy, has not yet been identified.We...
Paper Details
Title
Autoimmune Polyendocrine Syndrome Type 1 and NALP5, a Parathyroid Autoantigen
Published Date
Mar 6, 2008
Volume
358
Issue
10
Pages
1018 - 1028
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Notes
History