Freeze-Dried Mannitol for Superior Pulmonary Drug Delivery via Dry Powder Inhaler

Volume: 30, Issue: 2, Pages: 458 - 477
Published: Feb 1, 2013
Abstract
To show for the first time the superior dry powder inhaler (DPI) performance of freeze dried mannitol in comparison to spray dried mannitol and commercial mannitol. Different mannitol powders were sieved to collect 63–90 μm particles and then analyzed in terms of size, shape, surface morphology, solid state, density, flowability. Salbutamol sulphate-mannitol aerosol formulations were evaluated in terms of homogeneity, SS-mannitol adhesion, and...
Paper Details
Title
Freeze-Dried Mannitol for Superior Pulmonary Drug Delivery via Dry Powder Inhaler
Published Date
Feb 1, 2013
Volume
30
Issue
2
Pages
458 - 477
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