The multilayered complexity of ceRNA crosstalk and competition
Abstract
Recent reports have described an intricate interplay among diverse RNA species, including protein-coding messenger RNAs and non-coding RNAs such as long non-coding RNAs, pseudogenes and circular RNAs. These RNA transcripts act as competing endogenous RNAs (ceRNAs) or natural microRNA sponges — they communicate with and co-regulate each other by competing for binding to shared microRNAs, a family of small non-coding RNAs that are important...
Paper Details
Title
The multilayered complexity of ceRNA crosstalk and competition
Published Date
Jan 1, 2014
Journal
Volume
505
Issue
7483
Pages
344 - 352
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