Tissue distribution and urinary excretion of intravenously administered chemically functionalized graphene oxide sheets
Abstract
The design of graphene-based materials for biomedical purposes is of great interest. Graphene oxide (GO) sheets represent the most widespread type of graphene materials in biological investigations. In this work, thin GO sheets were synthesized and further chemically functionalized with DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid), a stable radiometal chelating agent, by an epoxide opening reaction. We report the tissue...
Paper Details
Title
Tissue distribution and urinary excretion of intravenously administered chemically functionalized graphene oxide sheets
Published Date
Jan 1, 2015
Journal
Volume
6
Issue
7
Pages
3952 - 3964
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History