Review paper
The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies
Abstract
Liver fibrosis results from dysregulation of normal wound healing, inflammation, activation of myofibroblasts and deposition of extracellular matrix (ECM). Chronic liver injury causes death of hepatocytes and formation of apoptotic bodies, which in turn, release factors that recruit inflammatory cells (neutrophils, monocytes, macrophages, and lymphocytes) to the injured liver. Hepatic macrophages (Kupffer cells) produce TGF1 and other...
Paper Details
Title
The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies
Published Date
Jul 22, 2014
Journal
Volume
5
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