The vast complexity of primary open angle glaucoma: Disease genes, risks, molecular mechanisms and pathobiology
Abstract
Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy triggered by both environmental and genetic risk factors. Several ocular tissues, including the ciliary body, trabecular meshwork and optic nerve head, and perhaps even brain tissues, are involved in a chain of pathological events leading to POAG. Genetic risk evidence for POAG came from family linkage-studies implicating a small number of disease genes (MYOC,...
Paper Details
Title
The vast complexity of primary open angle glaucoma: Disease genes, risks, molecular mechanisms and pathobiology
Published Date
Nov 1, 2013
Volume
37
Pages
31 - 67
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