The role of kinin B1receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents
Abstract
Objective
Verify the role of the kinin B1 receptors (B1R) and the effect of ACE inhibitors (ACEi) on acute gout induced by monosodium urate (MSU) crystals in rodents.Methods
Painful (overt pain and allodynia) and inflammatory parameters (joint oedema, leukocyte trafficking, interleukin-1β levels) of acute gout attacks were assessed several hours after an intra-articular injection of MSU (1.25 or 0.5...Paper Details
Title
The role of kinin B1receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents
Published Date
Oct 24, 2014
Volume
75
Issue
1
Pages
260 - 268
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Notes
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