Comprehensive molecular portraits of human breast tumours
Abstract
We analysed primary breast cancers by genomic DNA copy number arrays, DNA methylation, exome sequencing, messenger RNA arrays, microRNA sequencing and reverse-phase protein arrays. Our ability to integrate information across platforms provided key insights into previously defined gene expression subtypes and demonstrated the existence of four main breast cancer classes when combining data from five platforms, each of which shows significant...
Paper Details
Title
Comprehensive molecular portraits of human breast tumours
Published Date
Sep 23, 2012
Journal
Volume
490
Issue
7418
Pages
61 - 70
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Notes
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