The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer

Cutaneous hyperpigmentation occurs in multiple conditions. In addition, many Asian women desire a lighter skin colour. Thus, there is a need for the development of skin lightening agents. Niacinamide is a possible candidate.To investigate the effects of niacinamide on melanogenesis in vitro and on facial hyperpigmentation and skin colour in vivo in Japanese women.Melanin production was measured in a purified mushroom tyrosinase assay, cultured...