Protective effects of icariin on human umbilical vein endothelial cell injury induced by H2O2 in vitro

Icariin is a flavonoid isolated from Epimedium and is considered to be the major pharmacological active component of Epimedii Herba. In the present investigation, we studied and confirmed the protective activity of icariin on H2O2-induced injury in human umbilical vein endothelial cell line: ECV-304. Eighteen-hour treatment with 750 μmol l−1 H2O2 significantly decreased the viability of ECV-304 cells, which was accompanied with apparent...