Original paper
Differential effect of antioxidant treatment on plasma and tissue paraoxonase activity in hyperleptinemic rats
Abstract
Recent studies suggest that adipose tissue hormone, leptin, is involved in atherogenesis, especially in obese subjects. Previously, we have demonstrated that experimentally induced hyperleptinemia decreases plasma paraoxonase 1 (PON1) activity. The aim of this study was to investigate whether treatment with synthetic antioxidant, Tempol, modulates the effect of leptin on plasma and tissue PON1 in the rat. Leptin was administered at a dose of...
Paper Details
Title
Differential effect of antioxidant treatment on plasma and tissue paraoxonase activity in hyperleptinemic rats
Published Date
Jun 1, 2005
Journal
Volume
51
Issue
6
Pages
523 - 532
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Notes
History