CT Quantification of Large Opacities and Emphysema in Silicosis: Correlations among Clinical, Functional, and Radiological Parameters

Published on May 9, 2014in Lung2.584
· DOI :10.1007/S00408-014-9590-9
Marcos César Santos de Castro2
Estimated H-index: 2
(Federal Fluminense University),
Angela Santos Ferreira5
Estimated H-index: 5
(Federal Fluminense University)
+ 5 AuthorsEdson Marchiori52
Estimated H-index: 52
(UFRJ: Federal University of Rio de Janeiro)
Sources
Abstract
Background The assessment of the extent of silicosis on chest radiographs is subjective and could be more standardized by using computed tomography (CT) quantification methods. We propose a semiautomatic method of quantifying the anatomical lung damage (LD) (the sum of the emphysema and large opacities volumes) measured by CT densitovolumetry in complicated silicosis.
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References44
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#1Onno M. Mets (UU: Utrecht University)H-Index: 18
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Last. Jan Willem J. Lammers (UU: Utrecht University)H-Index: 41
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Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that is characterized by chronic airflow limitation. Unraveling of this heterogeneity is challenging but important, because it might enable more accurate diagnosis and treatment. Because spirometry cannot distinguish between the different contributing pathways of airflow limitation, and visual scoring is time-consuming and prone to observer variability, other techniques are sought to start this phenotyping process. Quantitat...
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Objectives To evaluate the prevalence of HRCT findings in construction workers previously surveyed by chest radiographs classified according to ILO guidelines. To examine the association between HRCT findings and exposure to quartz containing dust, and lung function. Methods The study comprised a questionnaire, dynamic and static lung function measurements, single-breath CO diffusion capacity, chest radiographs and HRCT in 79 individuals. Certified ‘B’ readers coded radiographs according to the ...
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#1Bruno Hochhegger (UFRJ: Federal University of Rio de Janeiro)H-Index: 29
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We compared whole-lung densitometry with visual evaluation of pulmonary emphysema. Thirty patients with chronic obstructive pulmonary disease underwent multi-detector CT (150 mAs and 0.75 collimation) with double reconstruction: thick (5-mm) slices with smooth filter for whole-lung densitometry and thin (1 mm) slices with sharp filter for visual assessment (one of every ten slices). Densitometry and visual assessment were performed by three operators each, and the time required for assessment, t...
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The severity of chronic obstructive pulmonary disease (COPD) is evaluated not only by airflow limitation but also by factors such as exercise capacity and body mass index. Recent advances in CT technology suggest that it might be a useful tool for evaluating the severity of the disease components of COPD. The aim of this study is to evaluate the correlation between the parameters measured on volumetric CT, including the extent of emphysema, air trapping, and airway thickening, and clinical param...
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