Original paper
Increased Expression of Glutathione Peroxidase 4 Strongly Protects Retina from Oxidative Damage
Abstract
Oxidative damage contributes to cone cell death in retinitis pigmentosa and death of rods, cones, and retinal pigmented epithelial (RPE) cells in age-related macular degeneration. In this study, we explored the strategy of overexpressing components of the endogenous antioxidant defense system to combat oxidative damage in RPE cells and retina. In transfected cultured RPE cells with increased expression of superoxide dismutase1 (SOD1) or SOD2,...
Paper Details
Title
Increased Expression of Glutathione Peroxidase 4 Strongly Protects Retina from Oxidative Damage
Published Date
Apr 1, 2009
Volume
11
Issue
4
Pages
715 - 724
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Notes
History