Metabonomics study of urine from Sprague–Dawley rats exposed to Huang-yao-zi using 1H NMR spectroscopy
Volume: 52, Issue: 1, Pages: 136 - 141
Published: May 1, 2010
Abstract
Urinary metabolic perturbations associated with liver toxicity induced by Huang-yao-zi (root of Dioscorea bulifera L.) were studied using nuclear magnetic resonance spectroscopy (1H NMR) to determine the correlations between metabonomic profiling and histopathologic/biochemical observations and to discover biomarkers for liver toxicity. Huang-yao-zi with a maximal tolerance dose (MTD) was given to male Sprague–Dawley rats for 72 h followed by...
Paper Details
Title
Metabonomics study of urine from Sprague–Dawley rats exposed to Huang-yao-zi using 1H NMR spectroscopy
Published Date
May 1, 2010
Volume
52
Issue
1
Pages
136 - 141
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