Original paper
Hematogenous Metastasis of Ovarian Cancer: Rethinking Mode of Spread
Abstract
Ovarian cancer has a clear predilection for metastasis to the omentum, but the underlying mechanisms involved in ovarian cancer spread are not well understood. Here, we used a parabiosis model that demonstrates preferential hematogenous metastasis of ovarian cancer to the omentum. Our studies revealed that the ErbB3-neuregulin 1 (NRG1) axis is a dominant pathway responsible for hematogenous omental metastasis. Elevated levels of ErbB3 in ovarian...
Paper Details
Title
Hematogenous Metastasis of Ovarian Cancer: Rethinking Mode of Spread
Published Date
Jul 1, 2014
Journal
Volume
26
Issue
1
Pages
77 - 91
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Notes
History