PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression
Abstract
Tissue factor (TF) (CD142) is a 47 kDa transmembrane cell surface glycoprotein that triggers the extrinsic coagulation cascade and links thrombosis with inflammation. Although macrophage TF expression is known to be regulated at the RNA level, very little is known about the mechanisms involved. Poly(adenosine 5'-diphosphate [ADP]-ribose)-polymerase (PARP)-14 belongs to a family of intracellular proteins that generate ADP-ribose posttranslational...
Paper Details
Title
PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression
Published Date
Dec 4, 2014
Journal
Volume
124
Issue
24
Pages
3646 - 3655
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