Enhanced osteoinduction by controlled release of bone morphogenetic protein-2 from biodegradable sponge composed of gelatin and β-tricalcium phosphate
Abstract
Biodegradable gelatin sponges at different contents of β-tricalcium phosphate (β-TCP) were fabricated to allow bone morphogenetic protein (BMP)-2 to incorporate into them. The in vivo osteoinduction activity of the sponges incorporating BMP-2 was investigated, while their in vivo profile of BMP-2 release was evaluated. The sponges prepared had an interconnected pore structure with an average pore size of 200 μm, irrespective of the β-TCP...
Paper Details
Title
Enhanced osteoinduction by controlled release of bone morphogenetic protein-2 from biodegradable sponge composed of gelatin and β-tricalcium phosphate
Published Date
Aug 1, 2005
Journal
Volume
26
Issue
23
Pages
4856 - 4865
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