Original paper
Long-Range Force Transmission in Fibrous Matrices Enabled by Tension-Driven Alignment of Fibers
Abstract
Cells can sense and respond to mechanical signals over relatively long distances across fibrous extracellular matrices. Recently proposed models suggest that long-range force transmission can be attributed to the nonlinear elasticity or fibrous nature of collagen matrices, yet the mechanism whereby fibers align remains unknown. Moreover, cell shape and anisotropy of cellular contraction are not considered in existing models, although recent...
Paper Details
Title
Long-Range Force Transmission in Fibrous Matrices Enabled by Tension-Driven Alignment of Fibers
Published Date
Dec 1, 2014
Journal
Volume
107
Issue
11
Pages
2592 - 2603
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Notes
History