Original paper
Effect of solution properties on the counting and sizing of subvisible particle standards as measured by light obscuration and digital imaging methods
Abstract
Protein formulations may contain subvisible particle (SbVP) impurities that can vary (e.g., in number, size, shape, density, refractive index and transparency) depending on the formulation composition, environmental stresses and the type of protein. Additionally formulation solutions may differ in their physical properties including turbidity, color, viscosity, density and refractive index. This study examined the impact of these formulation...
Paper Details
Title
Effect of solution properties on the counting and sizing of subvisible particle standards as measured by light obscuration and digital imaging methods
Published Date
Mar 1, 2014
Volume
53
Pages
95 - 108
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Notes
History