Sirtuin 1 activation enhances the PGC-1α/mitochondrial antioxidant system pathway in status epilepticus
Abstract
Sirtuin 1 (SIRT1) regulates numerous neuronal processes, including metabolism, antioxidation and aging, through activation of peroxisome proliferator-activated receptor coactivator 1-α (PGC-1α), an upstream regulator of mitochondrial biogenesis and function. However, the role of SIRT1 in the oxidative stress induced by seizures has yet to be elucidated. The present study aimed to investigate whether SIRT1 was involved in the activation of the...
Paper Details
Title
Sirtuin 1 activation enhances the PGC-1α/mitochondrial antioxidant system pathway in status epilepticus
Published Date
Oct 21, 2014
Journal
Volume
11
Issue
1
Pages
521 - 526
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History