A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
Abstract
Mitochondrial Ca(2+) homeostasis has a key role in the regulation of aerobic metabolism and cell survival, but the molecular identity of the Ca(2+) channel, the mitochondrial calcium uniporter, is still unknown. Here we have identified in silico a protein (named MCU) that shares tissue distribution with MICU1 (also known as CBARA1), a recently characterized uniporter regulator, is present in organisms in which mitochondrial Ca(2+) uptake was...
Paper Details
Title
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
Published Date
Jun 19, 2011
Journal
Volume
476
Issue
7360
Pages
336 - 340
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