RNA-protein interactions in the control of stability and localization of messenger RNA (review).

Growing evidence demonstrates the importance of regulating mRNA localization, stability and translation, in the control of gene expression, both in development and in differentiated cells. The signals responsible for specific regulation of mRNA metabolism reside in the RNA message itself: both 5' and 3' to the coding region, all transcripts contain variable lengths of untranslated sequences (5'-UTR and 3'-UTR) which contain the binding sites for...