Cognitive behavioral therapy

Sleep disorder

Cognition

Irritability

Psychiatry

Anxiety

Worry

Generalized anxiety disorder

Pharmacotherapy

Medicine

Annals of Internal Medicine

Generalized anxiety disorder (GAD) is a common and disabling illness that is often underdiagnosed and undertreated. Patients with GAD are at increased risk for suicide as well as cardiovascular-related events and death. Most patients can be diagnosed and managed by primary care physicians. Symptoms include chronic, pervasive anxiety and worry accompanied by nonspecific physical and psychological symptoms (restlessness, fatigue, difficulty concentrating, irritability, muscle tension, or sleep disturbances). Effective treatments include psychotherapy (often cognitive behavioral therapy) and pharmacotherapy, such as selective serotonin reuptake inhibitors and serotonin–norepinephrine reuptake inhibitors.

Generalized Anxiety Disorder