Original paper
Antiplasmodial activity of (I-3,II-3)-biflavonoids and other constituents from Ormocarpum kirkii
Abstract
Preliminary screening of a series of medicinal plants, traditionally used in Tanzania, showed an IC50 of 15.6–31.2 μg/ml for the crude extract of the root of Ormocarpum kirkii S. Moore (Papilionaceae) against Plasmodium falciparum. A bioguided isolation was performed in order to isolate the active constituents. Twelve constituents were obtained and identified using NMR and MS data, and optical rotation measurements. The compounds comprised seven...
Paper Details
Title
Antiplasmodial activity of (I-3,II-3)-biflavonoids and other constituents from Ormocarpum kirkii
Published Date
May 1, 2010
Journal
Volume
71
Issue
7
Pages
785 - 791
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Notes
History