Phytochemistry
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#1Luo Zhoufei (HAU: Hunan Agricultural University)
#2Xu Mengwei (HAU: Hunan Agricultural University)
Last. Xiao Langtao (HAU: Hunan Agricultural University)
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#1Carmina Sirignano (University of Naples Federico II)H-Index: 5
#2Saoussen HammamiH-Index: 10
Last. Orazio Taglialatela Scafati (University of Naples Federico II)
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Abstract Chemical analysis of the aerial parts obtained from a Tunisian specimen of Daucus carota yielded to the isolation of six undescribed polyoxygenated germacranes and one elemanolide, along with one known metabolite. The stereostructures of the undescribed compounds were determined by extensive spectroscopic analysis including 1D and 2D NMR and HR-ESI-MS analysis. Due to their structural similarity with the Plasmodium transmission-blocking agent daucovirgolide G, the isolated metabolites w...
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#1Xinhua Zhang (CAS: Chinese Academy of Sciences)H-Index: 11
#2Jaime A. da SilvaH-Index: 4
Last. Guohua Ma (CAS: Chinese Academy of Sciences)H-Index: 15
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Abstract Essential oils extracted from the heartwood of Indian sandalwood (Santalum album L.) contain linalool and nerolidol as minor components. However, nerolidol/linalool synthase (NES/LIS), which produce linalool and nerolidol, have yet to be characterized in sandalwood. Using a transcriptomic-based approach, a terpene synthase gene was screened from unigenes of transcriptome data derived from S. album seedlings exposed to low temperature (4 °C). The enzyme encoded by these complementary DNA...
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#1Chi Thanh MaH-Index: 2
#2Tu Loan Ly (Ton Duc Thang University)
Last. Jeong Hill Park (SNU: Seoul National University)H-Index: 7
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Abstract Nine undescribed sesquiterpenes, which include five guaiane and four humulene-type, were isolated from the agarwood of Aquilaria malaccensis. The structures of these undescribed sesquiterpenes were elucidated by spectroscopic methods including UV, HRESI-MS, 1D and 2D-NMR, ECD, and X-ray diffraction (Cu Kα). The isolated compounds were tested for their inhibitory effect against LPS-induced NO production in RAW 264.7 cells. In particular, one sesquiterpene (1α,7α-dihydroxy-8oxo-4αH,5αH-gu...
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#1Duaa Eliwa (University of Mississippi)
#2Mohamed A. Albadry (University of Mississippi)H-Index: 2
Last. Samir A. Ross (University of Mississippi)H-Index: 33
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The metabolism of papaverine, the opium benzylisoquinoline alkaloid, with Aspergillus niger NRRL 322, Beauveria bassiana NRRL 22864, Cunninghamella echinulate ATCC 18968 and Cunninghamella echinulate ATCC 1382 has resulted in O-demethylation, O-methylglucosylation and N-oxidation products. Two new metabolites (4″-O-methyl-β-D-glucopyranosyl) 4'-demethyl papaverine and (4″-O-methyl-β-D-glucopyranosyl) 6-demethyl papaverine, (Metabolites 5 and 6) together with 4'-O-demethylated papaverine (Metabol...
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#1Sayyedeh Fatemeh Askari (Birjand University of Medical Sciences)
#2Razieh Avan (Birjand University of Medical Sciences)H-Index: 3
Last. Samira Eghbali (Birjand University of Medical Sciences)
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Abstract Salvia is the largest genus of the Lamiaceae family, with over 900 species in the world which about 60 species are distributed in Iran, 17 of them are endemic. In Iran, Salvia species have been used to treat various diseases with a wide spectrum of pharmacological activity in vitro and in vivo. The present review summarizes the phytochemistry and pharmacology of medicinal Iranian Salvia species in order to describe their therapeutic potential for a range of diseases. . Phytochemical inv...
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#1Fa-Lei Zhang (SCUN/SCUEC: South Central University for Nationalities)H-Index: 3
#2Chen Shi (SCUN/SCUEC: South Central University for Nationalities)
Last. Ji-Kai Liu (SCUN/SCUEC: South Central University for Nationalities)H-Index: 32
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Abstract The chemical constituents and their biological activities of the mushroom Pyropolyporus fomentarius were investigated in this study. Two previously undescribed pentacyclic lupane-type triterpenes, 3-formyloxybetulin and 3-formyloxybetulinic acid, two rare degraded ergosterols, pyropolincisterols A and B, along with ten known triterpenoids and four known ergosterols were isolated from the fruiting bodies of P. fomentarius. Their chemical structures were determined using a combination of ...
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#1Xian-Li Zhou (GLMU: Guilin Medical University)H-Index: 2
#2Shan-Bin Li (GLMU: Guilin Medical University)
Last. Cheng-Qin Liang (GLMU: Guilin Medical University)H-Index: 2
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Abstract Thirteen undescribed dammarane triterpenoid saponins (cypaliurusides A–M), including eleven seco-dammarane type triterpenoids, were isolated from Cyclocarya paliurus. Each of these compounds has the unique feature of having a monosaccharide attached to C-11, rather than C-12, compared to the same type of saponins found in this plant. The structures of them were determined by comprehensive analysis of 1D, 2D NMR and HRESIMS data. Cypaliuruside J showed significant α-glucosidase inhibitor...
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#1Fatemeh Mohammadi (UT: University of Tehran)H-Index: 2
#2Mohammad Reza Naghavi (UT: University of Tehran)H-Index: 25
Last. Giuseppe Perretti (University of Perugia)H-Index: 18
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Abstract Variation in metabolism and partitioning of carbohydrates, particularly fructans, between annual and perennial Cichorium species remains a challenging topic. To address this problem, an annual (endive, Cichorium endive L. var. Crispum; Asteraceae) and a biennial species (chicory, Cichorium intybus L. var. Witloof; Asteraceae) were compared with in terms of variability in carbohydrate accumulation and expression patterns of fructan-active enzyme genes, as well as sucrose metabolism at va...
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#1Xiao-Cui Li (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 1
#2Fei Liu (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 3
Last. Liang Xiong (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 10
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Abstract Lanostane triterpenoids are thought to be the main underlying preclinical antitumor secondary metabolites of the genus Ganoderma. To further explore the potential cytotoxic triterpenoids from Ganoderma luteomarginatum, the ethyl acetate soluble fraction of 95% ethanolic extract was systematically studied. Twelve previously undescribed lanostane-type triterpene acids were isolated from the fruiting bodies of G. luteomarginatum, and their structures were elucidated by extensive spectrosco...
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