Phytochemistry
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4.07
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32.2k
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#1Yue-Hu Pei (HMU: Harbin Medical University)H-Index: 3
#2Li-Hua Zhang (TUTCM: Tianjin University of Traditional Chinese Medicine)H-Index: 1
Last. Gang Chen (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 7 authors...
Abstract null null Eight undescribed polyhydroxylated bergamotane-type sesquiterpenoids with bicyclic, tricyclic and tetracyclic systems, namely sporulamides A−D, sporulosoic acids A−B and sporuloketals A−B, along with three known analogs were isolated from cultures of the marine mud-associated fungus Paraconiothyrium sporulosum YK-03. The chemical structures of these sesquiterpenoids were elucidated by the extensive spectroscopic techniques of NMR and HR-ESI-MS. Assisted by the X-ray crystallog...
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#1Wei Hongli (CAS: Chinese Academy of Sciences)H-Index: 1
#2Yang Han (CAS: Chinese Academy of Sciences)H-Index: 2
Last. Xiuli Zhang (Soochow University)H-Index: 4
view all 12 authors...
Abstract null null A phytochemical investigation on chemical constituents from the rhizomes of Menispermum dauricum DC. identified eight undescribed dimeric alkaloids with structurally diverse monomeric isoquinoline. Alkaloid structures were elucidated by a combination of spectroscopic data analyses and time-dependent density functional theory (TDDFT) ECD calculation. The isolates were evaluated for inhibitory effect on dopamine D1 receptor and compound 1 exhibited potent D1 receptor antagonisti...
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#1Yang Hee Jo (CBNU: Chungbuk National University)H-Index: 13
#2Solip Lee (CBNU: Chungbuk National University)H-Index: 1
Last. Mi Kyeong Lee (CBNU: Chungbuk National University)H-Index: 21
view all 9 authors...
Abstract null null The composition of a plant, together with its efficacy, vary depending on its maturity and plant parts. In this study, the chemical constituents of immature fruits of Maclura tricuspidata (Moraceae) were investigated together with their anti-diabetic and antioxidant effects. A total of 34 compounds were isolated from the immature fruits of M. tricuspidata using various chromatographic methods. Structure elucidation using extensive spectroscopic analysis led to the characteriza...
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#1Rudolf Vrabec (Charles University)
#2Jana Maříková (Charles University)H-Index: 6
Last. Martina HrabinovaH-Index: 20
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Abstract null null One undescribed indole alkaloid together with twenty-two known compounds have been isolated from aerial parts of Vinca minor L. (Apocynaceae). The chemical structures of the isolated alkaloids were determined by a combination of MS, HRMS, 1D, and 2D NMR techniques, and by comparison with literature data. The NMR data of several alkaloids have been revised, corrected, and missing data have been supplemented. Alkaloids isolated in sufficient quantity were screened for their in v...
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#1Tonino G. Adessi (CONICET: National Scientific and Technical Research Council)H-Index: 1
#2Yamile Ana (UNC: National University of Córdoba)H-Index: 3
Last. Manuela E. García (CONICET: National Scientific and Technical Research Council)H-Index: 6
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Abstract null null This work focusses on the chemical diversification of an Ambrosia tenuifolia extract and its bioguided fractionation, aiming to unveil the chemical entity responsible for the trypanocidal activity. Besides, a revision of the phytochemical study of this species, based on previous reports of the antiparasitic psilostachyins A and C as main compounds, was conducted. To improve the biological properties of a plant extract through a simple chemical reaction, the oxidative diversifi...
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#1Ya-Ping Huang (NJUCM: Nanjing University of Chinese Medicine)H-Index: 1
#2Yun-Shan Wang (NJUCM: Nanjing University of Chinese Medicine)H-Index: 1
Last. Ke Pan (CPU: China Pharmaceutical University)H-Index: 10
view all 9 authors...
Abstract null null Seven undescribed dammarane-type saponins, gypenosides LXXXI-LXXXVII, together with four known compounds, were isolated from the whole herb of Gynostemma pentaphyllum. The chemical structures of these undescribed compounds were elucidated on the basis of physical and spectroscopic analysis and comparison with literature data. All the isolates were evaluated for their proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitory activities in HepG2 cells. Among them, gypenos...
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#1Muyuan Yu (HUST: Huazhong University of Science and Technology)H-Index: 2
#2Xin Kang (HUST: Huazhong University of Science and Technology)H-Index: 2
Last. Yonghui Zhang (HUST: Huazhong University of Science and Technology)H-Index: 30
view all 9 authors...
Abstract null null Eight undescribed cyathane diterpenoids, representative specialised metabolites of the genus Cyathus, named cyathins Q–X, along with five known congeners, were isolated from the liquid fermentation of Cyathus africanus. Their structures and absolute configurations were elucidated by integrating NMR spectroscopic analyses, electronic circular dichroism (ECD) calculations, and X-ray diffraction. Reasonable correction to the C-12 configuration of cyathin I was corroborated by the...
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#1Wen-Chao Tu (CAS: Chinese Academy of Sciences)H-Index: 4
#2Lin-Fen Ding (KMU: Kunming Medical University)H-Index: 6
Last. Qin-Shi Zhao (CAS: Chinese Academy of Sciences)H-Index: 30
view all 6 authors...
Abstract null null Ten previously undescribed cassane diterpenoids, cassabonducins A–J, and eleven known compounds were isolated from the seeds of Caesalpinia bonduc. The structures of the undescribed compounds were elucidated by extensive analysis of spectroscopic data (IR, HRESIMS, and 1H, 13C and 2D NMR) and their absolute configurations were determined by the ECD data and single-crystal X-ray diffraction analysis. e-Caesalpin-Ⅶ was obtained from natural resources for the first time. Cassabon...
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#1Chen Qian-wen (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)
#2Ye Xiao (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)
Last. Wang Zhimin (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 2
view all 7 authors...
Abstract null null Picrasma quassioides, a member of the Simaroubaceae family, is the subject of research in numerous pharmacological and chemical studies. This plant mainly contains alkaloids, quassinoids and terpenoids. These molecules exhibit various pharmacological benefits, such as anti-inflammatory, anticancer, and anti-viral effects, on the cardiovascular system. Alkaloids make up the majority of these molecules. This review describes 127 alkaloid substances from P. quassioides. These alk...
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#1Yi-Jie Zhai (Northwest A&F University)H-Index: 2
#2Guang-Ming HuoH-Index: 1
Last. Jin-Ming Gao (Northwest A&F University)H-Index: 32
view all 9 authors...
In this research, twenty aromatic and branched aliphatic polyketides, including seven previously undescribed butenolide derivatives, piterriones A–G and one known analogue, along with twelve known altenusin derivatives, were isolated from the isopod-associated fungus Pidoplitchkoviella terricola. Their structures were elucidated by analysis of NMR (1D and 2D) and mass spectrometry data, and their absolute configurations were determined by Mosher's method, microscale derivatization, and compariso...
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