Adjuvant chemotherapy for the perineural invasion of colorectal cancer

Background To evaluate the association of perineural invasion (PNI) with outcomes in patients after colorectal resection of colorectal cancer (CRC) and to assess the effect of PNI on the response to adjuvant chemotherapy. Patients and methods Data were retrospectively reviewed for 178 patients with consecutive stages I–III CRC who underwent curative surgery between January 1999 and December 2004. PNI data were examined, and the overall survival...