A Comparison of Retinal Morphology Viewed by Optical Coherence Tomography and by Light Microscopy

Objective:

To compare the cross-sectional images of primate retinal morphology obtained by optical coherence tomography (OCT) with light microscopy to determine the retinal components represented in OCT images.

Methods:

Laser pulses were delivered to the retina to create small marker lesions in aMacaca mulatta. These lesions were used to align in vivo OCT scans and ex vivum histologic cross sections for image comparison....