Insulin‐independent glucose transport regulates insulin sensitivity

The glucose transport proteins (GLUT1 and GLUT4) facilitate glucose transport into insulin‐sensitive cells. GLUT1 is insulin‐independent and is widely distributed in different tissues. GLUT4 is insulin‐dependent and is responsible for the majority of glucose transport into muscle and adipose cells in anabolic conditions. We suggest the hypothesis that insulin resistance is dependent on whether glucose is entering through GLUT1 or GLUT4 and on...