Mapping of the Neonatal Fc Receptor in the Rodent Eye

purpose. The neonatal Fc receptor (FcRn) has been known to modulate IgG transport and protect against IgG catabolism, resulting in extension of the serum half-life of IgG. The goal of this study was to localize FcRn receptor expression in the rat’s eye. methods. The cornea, retina, conjunctiva, ciliary body and iris, retinal pigment epithelium and choroid, and lens were dissected from each rat’s eye, and total RNA was purified. The first-strand...