Original paper
Direct Visualization of Macrophage-Assisted Tumor Cell Intravasation in Mammary Tumors
Abstract
Although the presence of macrophages in tumors has been correlated with poor prognosis, until now there was no direct observation of how macrophages are involved in hematogenous metastasis. In this study, we use multiphoton microscopy to show, for the first time, that tumor cell intravasation occurs in association with perivascular macrophages in mammary tumors. Furthermore, we show that perivascular macrophages of the mammary tumor are...
Paper Details
Title
Direct Visualization of Macrophage-Assisted Tumor Cell Intravasation in Mammary Tumors
Published Date
Mar 15, 2007
Journal
Volume
67
Issue
6
Pages
2649 - 2656
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Notes
History