Bronchial Hyperresponsiveness and Toluene Diisocyanate
Abstract
Long-term change in nonspecific and specific bronchial hyperresponsiveness was studied in 16 subjects with asthma induced by toluene diisocyanate (TDI). A significant positive correlation between months of follow-up and provocative dose inducing a 20 percent fall in FEV1 (PD20FEV1) methacholine was observed in 5 of 16 subjects. In 4 of these 5 subjects, a PD20FEV1 > 1 mg of methacholine was observed 30 to 48 months after the end of TDI exposure....
Paper Details
Title
Bronchial Hyperresponsiveness and Toluene Diisocyanate
Published Date
Apr 1, 1993
Journal
Volume
103
Issue
4
Pages
1123 - 1128
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Notes
History