Relationship between Serum Heat-Stable Neutrophil Chemotactic Activity during Early Airway Reaction to Allergen and the Pattern of Airway Response (Early versus Late Reactions) in Asthmatic Subjects

In order to evaluate the relationship between allergen-induced heat-stable neutrophil chemotactic activity (HS-NCA) release during early asthmatic reaction (EAR) and the presence of a late asthmatic reaction (LAR), serum HS-NCA was measured at three serum dilutions (1:5, 1:40, 1:200) during EAR induced by allergen in 26 atopic asthmatics, 13 with isolated EAR and 13 with EAR followed by LAR. HS-NCA was measured using a 48-well microchamber with...