Fl Dente
University of Pisa
AirwayInternal medicineImmunologyAllergyPlaceboAsthmaRespiratory diseaseBronchial hyperresponsivenessSputumInhalationEosinophilOccupational asthmaAllergenBronchoconstrictionMethacholineHypertonic salineAnesthesiaMedicinePulmonary function testingEosinophil cationic proteinGastroenterology
53Publications
19H-index
924Citations
Publications 53
Newest
#1Ml Bartoli (UniPi: University of Pisa)H-Index: 10
#2Elena Bacci (UniPi: University of Pisa)H-Index: 27
Last. Pierluigi Paggiaro (UniPi: University of Pisa)H-Index: 48
view all 9 authors...
predict the quality of the sputum samples obtained in a large group of asthmatic subjects. Methods. We compared the presence of sputum productive cough in the days preceding the test, easiness in expectoration during the test, and sputum macroscopic aspect (presence of visible plugs) with the quality of slides obtained from sputum processing. We also monitored changes in the quality in patients who repeated sputum collection several times, comparing those whose first sample was adequate with tho...
1 CitationsSource
#1Silvana Cianchetti (UniPi: University of Pisa)H-Index: 23
#2Elena Bacci (UniPi: University of Pisa)H-Index: 27
Last. Pierluigi Paggiaro (UniPi: University of Pisa)H-Index: 48
view all 14 authors...
SummaryBackground Sputum eosinophil counts and eosinophil cationic protein (ECP) levels are usually increased in asthmatic patients. The correlation between sputum eosinophils or ECP and clinical findings of asthma has been previously investigated but many of these studies have been performed on small samples of asthmatic patients, considering only few clinical indices and often including patients on oral or inhaled corticosteroids, which might be confounding when interpreting the relationship b...
10 CitationsSource
Background: Long-term follow-up of diisocyanate-induced occupational asthma has been occasionally reported. Methods: We studied the outcome of toluene diisocyanate (TDI)-induced asthma in 46 patients at diagnosis and after a follow-up of 11 ± 3.6 years. Symptoms, anti-asthma therapy, forced expiratory volume in 1 s (FEV1) and bronchial hyperresponsiveness to methacholine were assessed. Results: A significant improvement in FEV1 (% predicted) and PD20FEV1 methacholine was observed at follow-up in...
6 CitationsSource
#1D Talini (UniPi: University of Pisa)H-Index: 13
#2Federica NovelliH-Index: 11
Last. P.L. PaggiaroH-Index: 14
view all 10 authors...
Background: Few data are reported on the effects of a reduction of exposure to specific sensitizers in occupational asthma (OA). The objective of this study was to evaluate the clin
8 CitationsSource
#1Ml Bartoli (UniPi: University of Pisa)H-Index: 10
#2Federica NovelliH-Index: 11
Last. P.L. Paggiaro (UniPi: University of Pisa)H-Index: 14
view all 11 authors...
Background. Oxidative stress plays a role in the pathogenesis of many chronic inflammatory lung diseases. Exhaled breath condensate (EBC) collection is a noninvasive method to investigate pulmonary oxidative stress biomarkers such as malondialdehyde (MDA). Subjects and Methods. We measured MDA levels in EBC in a large number of patients () with respiratory diseases: asthma (), bronchiectasis (BE, ), chronic obstructive pulmonary disease (COPD, ), idiopathic pulmonary fibrosis (IPF, ). Fourteen h...
88 CitationsSource
#1Elena Bacci (UniPi: University of Pisa)H-Index: 27
#2Lorenza Melosini (UniPi: University of Pisa)H-Index: 5
Last. Pierluigi Paggiaro (UniPi: University of Pisa)H-Index: 48
view all 8 authors...
Background. Since 1995 GINA (Global Initiative on Asthma) guidelines for asthma management have been updated annually and published in order to promote better management of asthma in real life situations. The aim of our study was to assess the level of implementation of GINA Guidelines among Italian Pulmonary Specialists (PSs). Methods. A detailed questionnaire was sent to 296 Respiratory Units (RUs) in Italy in order to collect information about personnel involved in the management of asthma pa...
Source
#1D TaliniH-Index: 13
#2Federica Novelli (UniPi: University of Pisa)H-Index: 11
Last. Pierluigi PaggiaroH-Index: 48
view all 9 authors...
Occupational asthma (OA) is a heterogeneous disease, and the characteristics of the sensitizer responsible for OA may induce different clinical, functional, and biological manifestations. We examined the characteristics of 74 patients with OA induced by low molecular weight compounds (LMWC) or by high molecular weight compounds (HMWC) and diagnosed by specific inhalation challenge (SIC). Patients with OA induced by LMWC had a longer occupational exposure before the beginning of symptoms, a lower...
12 CitationsSource
#1Chiara BaldiniH-Index: 37
#2S. GrossiH-Index: 1
Last. Stefano BombardieriH-Index: 84
view all 10 authors...
Apr 1, 2009 in ATS (American Thoracic Society International Conference)
#1Fl DenteH-Index: 19
#2Laura Malagrinò (UniPi: University of Pisa)H-Index: 9
Last. P.L. PaggiaroH-Index: 14
view all 10 authors...
Source
Apr 1, 2009 in ATS (American Thoracic Society International Conference)
#1Elena Bacci (UniPi: University of Pisa)H-Index: 27
#2Lorenza Melosini (UniPi: University of Pisa)H-Index: 5
Last. P.L. PaggiaroH-Index: 14
view all 9 authors...
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