The role of adipose-derived stem cells in endometrial cancer proliferation

Obesity has been identified as a key risk factor for the development of endometrial cancer (EC), the most common gynecologic malignancy in the US. We hypothesized that adipose tissue from EC patients secretes higher levels of cancer-promoting factors than healthy adipose tissue and promotes tumor cell growth.In this study, we generated conditioned media from adipose-derived stem cells (ASCs), an important regenerative cell population within...