Metabonomic study of biochemical changes in the urine of Morning Glory Seed treated rat

This paper was designed to study metabonomic characters of the nephrotoxicity induced by Morning Glory Seed (MGS), a well-known traditional Chinese medicine which was used for the treatment of edema, simple obesity and lung fever. Urinary samples from control and MGS treated rats were analyzed by ultra-performance liquid chromatography/mass spectrometry (UPLC–MS) in positive ionization mode. Blood biochemistry and histopathology were examined to...