Inhibitory effects of methotrexate on spontaneous motility and Cajal-like type of tubal interstitial cells in rabbit oviduct
Abstract
ObjectiveTo study the adverse biomechanical effects of methotrexate (MTX) on spontaneous tubal motility and on a widely distributed Cajal-like type of tubal interstitial cells (t-ICC) in rabbits. In our previous study, MTX was confirmed to cause acute endosalpingitis, and ultrastructural and steroid receptor damage in rat's endosalpinx in a dose-dependent manner.DesignDifferences in spontaneous tubal contractions and cellular distribution of...
Paper Details
Title
Inhibitory effects of methotrexate on spontaneous motility and Cajal-like type of tubal interstitial cells in rabbit oviduct
Published Date
Jul 1, 2012
Journal
Volume
98
Issue
1
Pages
215 - 221
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Notes
History