Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons

Laminin-332 is a major component of the dermo-epidermal skin basement membrane and maintains skin integrity. Here the authors find that it also suppresses a mechanosensitive current by preventing the formation of protein tethers required for current activation and exerts local control of over sensory axon branching behavior. Laminin-332 is a major component of the dermo-epidermal skin basement membrane and maintains skin integrity. The...