Incorporation of magnetic resonance imaging into intensity modulated whole-pelvic radiation therapy treatment planning to reduce the volume of pelvic bone marrow irradiated

Intensity modulated radiation therapy (IMRT) has been used to reduce the volume of small bowel irradiated in gynecology patients. We are currently exploring IMRT as a means of reducing the volume of pelvic bone marrow (BM) irradiated and thus the risk of hematologic toxicity in this patient group. While CT is commonly used for treatment planning, it is not sensitive enough to distinguish between active and nonactive BM. The purpose of this study...