Abstract 1081: Expression of TGFβ3 and its effects on migratory and invasive behavior in prostate cancer cells: Involvement of PI3K/Akt pathway

Transforming Growth Factor-β (TGFβ) is a secreted protein that is involved in the regulation of many cellular processes and has been implicated as a factor in cancer cell invasion and metastasis. Studies have indicated that different TGFβ isoforms may exert differential effects on cancer cells during different stages of the disease, however very little is known about the expression patterns of the 3 isoforms in prostate cancer. Non-traditional...