Original paper
Study of Antimalarial Activity of Chemical Constituents from Diospyros quaesita
Abstract
Bioassay-directed fractionation led to the isolation of seven compounds from a sample of the dried leaves, twigs, and branches of Diospyros quaesita Thw. (Ebenaceae). One of the isolates, betulinic acid 3-caffeate (1), showed in vitro antimalarial activity against Plasmodium falciparum clones D(6) (chloroquine-sensitive) and W(2) (chloroquine-resistant) with IC(50) values of 1.40 and 0.98 microM, respectively. Evaluation of compound 1 in the...
Paper Details
Title
Study of Antimalarial Activity of Chemical Constituents from Diospyros quaesita
Published Date
Nov 1, 2008
Journal
Volume
5
Issue
11
Pages
2442 - 2448
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Notes
History