Original paper
Acid‐sensing ion channel 1: A novel therapeutic target for migraine with aura
Abstract
Objective: Migraine with aura is a severe debilitating neurological disorder with few relatively specific therapeutic options. Methods: We used amiloride, a blocker of epithelial sodium channels, to evaluate its pharmacological potential and explored the biology of a potential mechanism of action in well‐established experimental models. Results: Amiloride was shown to block cortical spreading depression, the experimental correlate of aura, and...
Paper Details
Title
Acid‐sensing ion channel 1: A novel therapeutic target for migraine with aura
Published Date
Oct 1, 2012
Journal
Volume
72
Issue
4
Pages
559 - 563
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Notes
History