Original paper
Abstract 2475: Zpo2 promotes aggressive breast cancer development through downregulation of GATA3
Abstract
Metastatic breast cancer is the major cause of poor prognosis and death in women. The transcription factor GATA3 is a key mediator of luminal cell fate determination and homeostasis in adult mammary gland. Loss of GATA3 has been associated with development of metastatic mammary tumors. Here we describe a novel role for transcriptional repressor, Zeppo2 (zinc finger elbow-related proline domain protein2; Zpo2) (ZNF503) in promoting metastatic...
Paper Details
Title
Abstract 2475: Zpo2 promotes aggressive breast cancer development through downregulation of GATA3
Published Date
Oct 1, 2014
Journal
Volume
74
Issue
19_Supplement
Pages
2475 - 2475
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Notes
History