Prediction of adverse perinatal outcome by maternal serum screening for down syndrome in an asian population

To investigate the association between adverse perinatal outcomes and abnormal elevations of serum marker levels (alpha-fetoprotein [AFP] and free β-hCG) or a false-positive screen for Down syndrome. Pregnancy outcome information was available for 5885 Taiwanese women under 35 years of age who had second-trimester maternal serum screening for Down syndrome, using AFP and free β-hCG, and delivered a chromosomally normal fetus. Those with AFP at...