Salvage of Locally Recurrent Prostate Cancer After Definitive Radiotherapy

Although a significant proportion of patients with localized prostate cancer are cured after definitive radiotherapy, solitary local recurrence is observed in a subset of patients and poses a management challenge. Curative-intent treatment options include prostatectomy, reirradiation, cryotherapy, and high-intensity–focused ultrasound. Outcomes data after any of these options are relatively limited. The 5-year biochemical progression-free...